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When blood glucose levels return to normal, the incretin effect diminishes, maintaining blood glucose at normal levels with high safety (60, 61)

Adicionalmente, GLP-1 asegura que las reservas de insulina de las clulas beta pancreticas estn llenas, previniendo el agotamiento durante la secrecin al promover la transcripcin del gen de la insulina, estabilidad del ARNm y biosntesis

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