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d ) Western blots showing BRD4 degradation in HEK293T (with low level of YPEL5 expression: YPEL5 low ) or TC-71 (with elevated level of YPEL5 expression: YPEL5 high ) cells treated with 2 M ZZ1 for 5 h
In this way, two toxic species, superoxide radical and hydrogen peroxide, are converted to the harmless product water
Two anti-obesity agents, lorcaserin and the combination of phentermine and topiramate, have been shown to improve glycemic control in obese individuals with type 2 diabetes

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