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Another momentous reason for OS is the overproduction of free radicals due to mitochondrial dysfunction (Schieber and Chandel, 2014)
411429, 2014 [9] I
So far, eight isoforms of Gpx have been identified in humans, which vary in cellular location and substrate specificity (Mari et al., 2009), which in the liver account for about one third of the total Gpx activity ( 2 O 2 and has been classically believed to be the major H 2 O 2 reducing enzyme
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