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This is achieved by replacing and modifying specific amino acids in human GLP-1
Mild peripheral edema (ankle swelling, a sensation of puffiness in hands) occurs in approximately 15 to 20% of patients initiating therapy and typically resolves within 2 to 4 weeks as the body adapts 13
"Lilly's Once-Weekly Dulaglutide Shows Non-Inferiority to Liraglutide in Head-to-Head Phase III Trial for Type 2 Diabetes" (Press release)
Topical application studies report minimal adverse effects
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