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Description

The underlying mechanism for the increased HR has not yet been fully elucidated

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& Ward, J

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FDA-approved as Mounjaro (diabetes) and Zepbound (obesity)

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Recent Developments: 2025: Eli Lilly received FDA approval for tirzepatide (Zepbound) as a treatment for moderate-to-severe obstructive sleep apnea in adults with obesity the first pharmacotherapy approved for this indication expanding tirzepatide's approved uses beyond metabolic conditions into a respiratory indication affecting over 30 million Americans and supported by SURMOUNT-OSA trial data showing 63% reduction in apnea-hypopnea index

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