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Taken as a once-weekly injection Doses studied so far include: 1 mg, 4 mg, 8 mg, and up to 12 mg Gradual dose increases are used to help the body adjust and reduce side effects Because retatrutide is still in development, the exact dosing schedule could change before it becomes available, but the general approach is expected to feel similar to current GLP-1 medications
Very little of the methylene blue was eliminated in the urine either intact or as leukomethylene blue in spite of its relatively short half life
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