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62 Collectively, the evidence supports a mechanism-informed, risk-stratified clinical approach that prioritises gradual dose escalation, anticipatory counselling, functional monitoring, and targeted vigilance in susceptible subgroups, while recognising persistent evidence gaps and the need for long-term, high-quality, real-world safety data to characterise uncommon and delayed adverse outcomes associated with GLP-1 receptor agonists
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If GLP-1s are interfering with your intuitive eating practices, Smith recommends reaching out to your prescribing physician and an eating disorder professional to reassess whether the potential benefits are worth the risks
In research settings, it has been observed to increase pigmentation and modulate central pathways influencing libido and appetite
