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However, the absence of face-to-face interactions with clinicians limits the scope of services

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No published trials compare outcomes between standard-start and loading-dose regimens

In the Phase I clinical trial, nausea was dose-limiting at 0.025 mg/kg (approximately 1.75 mg for a 70 kg person) notably, this is the same dose later used for PT-141's FDA approval (Dorr et al., 1996)