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This dose and time regiment was chosen as has been shown to be well-tolerated in mice while producing measurable biological effects on the mitochondria (Xia et al., 2011)

Phentermine generally produces more weight loss but requires a prescription and is short-term only

In mouse models of obesity (diet-induced obesity: DIO), levels of FGF15 (the mouse ortholog of human FGF19) are reduced and in humans, serum levels of FGF19 are found to be significantly reduced in patients with type 2 diabetes

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