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You shouldnt take semaglutide if you: Have a personal or family history of medullary thyroid carcinoma (MTC), a type of thyroid cancer Have multiple endocrine neoplasia syndrome type 2 (MEN2), a rare, inherited condition that causes tumors Have an allergy to any of the ingredients in semaglutide drugs Are taking another semaglutide medication or glucagon-like peptide-1 ( GLP-1 ) receptor agonist (like liraglutide, for example) Let your healthcare provider know about any health problems you currently have (or previously had), including: Type 2 diabetes and a history of diabetic retinopathy (an eye condition) Depression, suicidal thoughts, or any other mental health issue Problems with your kidneys, gallbladder, or pancreas, such as gallbladder disease or a history of pancreatitis Some of these things wont automatically disqualify you from getting semaglutide, but a healthcare professional may want to keep a closer eye on you throughout your treatment

If you experience an erection that lasts more than four hours, seek emergency medical care immediately to avoid lasting harm

For example, if you want 1mg total and you have one vial at 5mg/mL and another at 2.5mg/mL, you could draw 10 units from the 5mg/mL vial to get 0.5mg and then draw 20 units from the 2.5mg/mL vial to get another 0.5mg, totaling 30 units for 1mg

This step-up should happen after at least four weeks at the current dose