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Bacteria can grow inside, making it unsafe for future use
Treatment is provided under medical supervision and tailored to individual health goals
thus, resistant peptic ulcers equal to resistant chronic skin ulcers, both unable to heal (Skorjanec et al., 2009)
Assuming a 1:1:1 group allocation ratio, a sample size of 29 teeth per group was required to achieve 80% power to detect between-group differences
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