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The pathogenesis of RIP involves multiple pathological processes, including radiation-induced excessive production of reactive oxygen species (ROS), leading to oxidative stress, which in turn triggers apoptosis and mucosal barrier disruption, as well as an inflammatory cascade centered on proinflammatory cytokines
Pancreatitis , though rare, represents a serious potential adverse effect
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J Am Board Fam Med November-December 2009 vol
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