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After oral doses of 1-6 g, the absolute bioavailability is 5-18%
These mechanisms together explain the impressive results seen in clinical trials
According to the Summary of Product Characteristics (SmPC), the most common side effects include: Nausea (affecting 12-24% of patients, with frequency increasing at higher doses) Diarrhoea (reported in 13-22% of participants) Vomiting (occurring in 6-10% of patients) Constipation (affecting 5-12% of users) Abdominal pain or discomfort Dyspepsia (indigestion) Decreased appetite These effects are typically mild to moderate in severity and tend to diminish over time as the body adjusts to treatment
These changes dont rely on medications but are key for losing weight and staying healthy, as they tackle some of the underlying reasons for obesity
