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For patients already on venlafaxine at doses 150 mg/day (where NET inhibition becomes clinically relevant), adding an uncharacterized vasopressive modulator creates a monitoring burden that cannot be managed without serial blood pressure measurement

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These may include: structured exercise programs weight management where appropriate physiotherapy activity modification medications when clinically indicated regenerative medicine approaches in carefully selected patients Research exploring BPC-157 has generated interest because of its potential influence on inflammation and tissue repair