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When combined with radiotherapy and PD-1 blockade, these nanoparticles promote CD8+ T cell infiltration and activate antitumor immune responses, demonstrating the potential of metal-based nanoplatforms to synergize with multiple therapeutic modalities (57) ( Figure 2 )

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What all of this could mean for the Keytruda crossover According to Evaluates consensus forecast, Keytruda maintains its crown through 2028 at approximately $30 billion, with Mounjaro trailing at $17 billion