Its combination with trastuzumab further enhances anti-tumor activity, inducing ROS accumulation and promoting apoptosis in SK-OV3 and BT-474 cells, thereby significantly improving the therapeutic effect [111] (Table 3)
Future studies should confirm these outcomes in larger, stratified cohorts, assess long-term effects, and delineate the immunomodulatory molecular pathways through which GSH-C4 influences the ocular surface
In addition, liver-derived acylcarnitine can also be taken up by intestinal epithelial cells and used for mitochondrial oxidative metabolism, providing additional energy for intestinal cells [218]
Svagusa T, Sikiric S, Milavic M, Sepac A, Seiwerth S, Milicic D, et al