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Someone with a specific GLP1R variant might feel full and lose weight steadily at 1 mg, while another person with a different genetic profile may need 2.4 mg to reach similar appetite suppression

As Novo Nordisk and Lilly keep expanding their obesity portfolios, their respective new assets with novel MoAs, some of which are expected to enter the market in the next 3 years, will need to be optimally (co-)positioned, in the context of both each players own portfolio and against the wider market

Those who have heart or thyroid problems, or who take medications that affect the heart, may need extra care and follow-up

Carrying excess body weight increases systemic inflammation and alters hormone levels that can trigger migraines, particularly in women