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When GLP-1 activates these brain regions, two things happen: You feel full and satisfied, and naturally stop wanting to eat more High-calorie, high-sugar foods feel less appealing the craving for them is turned down A 2014 study used brain scans (fMRI) to show this happening in real time in human volunteers GLP-1 receptor activation actually reduced brain activity in the regions that process hunger and food rewards

A good starting point is around 1.2 to 1.6 g/kg/day, or about 0.54 to 0.73 g/lb, depending on tolerance

Understanding why GLP-1 therapy works for PCOS requires looking at the metabolic drivers behind the condition

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