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In laboratory and pre-clinical settings, DSIP has been studied as a uniquely multifunctional endogenous regulatory neuropeptide across sleep, stress, neuroendocrine, neuroprotection, and geroprotective research applications: Sleep biology delta-wave SWS promotion, sleep homeostasis modulation, sleep efficiency and sleep latency research Sleep EEG research delta-wave induction, SWS vs REM sleep architecture, and sleep stage analysis via polysomnography Sleep neuromodulator pharmacology DSIP vs sedatives and hypnotics

mild, moderate, severe, and very severe ( In one survey of 1418 ME/CFS patients ( Diagnostic criteria for ME/CFS The original neurological classification of ME/CFS In 1969, the World Health Organisation (WHO) classified ME/CFS as a neurological disease ( Available diagnostic criteria Despite its high prevalence, there are still no universally accepted clinical criteria to characterise ME/CFS, making early and accurate diagnosis difficult ( Figure 3

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Fortunately, these agents have a relatively wide therapeutic index