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Combinations such as angiotensin receptor-neprilysin inhibitors and mineralocorticoid receptor antagonists fail to achieve statistically significant improvements in key HFpEF outcomes
doi: 10.1016/j.tifs.2020.07.002 3 AhlawatY.LiS.TimilsenaP
Higher body weight is independently associated with increased reflux risk because abdominal fat places additional pressure on the stomach
The U.S Food and Drug Administration initially rejected it after it appeared to cause several types of tumors in rats, but when a one-year human trial showed no apparent cancer, it was approved, and went on to become one of the most frequently prescribed weight-loss drugs
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