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Although there is no well-accepted gold standard for confirming vitamin B12 deficiency (92), there are two somewhat complementary primary methods of assessing vitamin B12 status: (1) directly measuring vitamin B12 levels in the serum and (2) measuring levels of metabolites that accumulate as a result of inadequate vitamin B12

Their major strength lies in the fact that the pupils' theoretical and technological studies find immediate application, being carried into practice through the radio base and the student broadcasting service

Of particular note, knockdown of the gene BDH1 , which mediates ketolysis (Fig

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