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Volume of distribution calculations from pharmacokinetic studies indicate extensive tissue distribution beyond the vascular compartment
The enzyme nicotinamide phosphoribosyltransferase (Nampt) converts nicotinamide to nicotinamide adenine mononucleotide (NMN) and is then converted into NAD+ using another enzyme known as nicotinamide mononucleotide adenylyltransferase (Nmnat)
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