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Patients who have lost significant weight often have thinner, less elastic skin with reduced dermal collagen
No published mechanistic study has examined how the fragment interacts with growth-plate chondrocytes, hypothalamic GHRH neurons, or pubertal steroidogenesis
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This metabolic activity makes visceral fat a frequent measurement point in growth-hormone pathway research, since compounds studied for their effect on endogenous growth hormone release are often evaluated specifically against visceral fat mass rather than total body fat
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