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Metformin reduces hepatic glucose production and improves insulin sensitivity in muscle tissue, while GLP-1 drugs slow gastric emptying and enhance pancreatic insulin secretion
As soon as Mojsov and Deanna Deery, Weir's technician, injected the peptide into the perfused rat, they were astonished to see it secrete insulin, even when given in a tiny dose, the same concentration as the one that circulates in the blood
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Torres-Collado L et al
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