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The body's absorption mechanism involves intrinsic factora glycoprotein secreted by gastric parietal cellswhich facilitates absorption of approximately 1.52 micrograms per meal in the terminal ileum, with additional amounts absorbed through passive diffusion at about 1% of the remaining dose

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Free Cu2+ is toxic (Fenton reactions, hydroxyl radicals), but the GHK-Cu complex is stable, diffusible and delivers copper in a targeted manner to copper-dependent metalloenzymes: lysyl oxidase (collagen/elastin crosslinking), Cu/Zn superoxide dismutase (SOD1, antioxidant defence), tyrosinase (controlled melanogenesis), dopamine-beta-hydroxylase

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