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It is a structured refeed that targets specific hormonal mechanisms, particularly leptin resensitization
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It creates a feeling of fullness, leading to a natural reduction in caloric intake
Yes, with a clear dose-response relationship: 0.25 mg dose: 9-11% constipation rate 0.5 mg dose: 12-14% constipation rate 1.0 mg dose: 15-18% constipation rate 2.4 mg dose: 23-24% constipation rate The increase from 0.5 mg to 2.4 mg roughly doubles the constipation risk
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