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In fact, a 2008 study found that after taking a 1,000 mcg oral supplement, only approximately 1.3% (or 13 mcg) of B12 was absorbed into the bloodstream
These mitochondrial alterations are accompanied by changes in nuclear-encoded mitochondrial gene expression, suggesting epigenetic regulation of cellular energy metabolism pathways (49)
10.2174/13816128113190990411 64 SikiricP.SeiwerthS.RucmanR.TurkovicB.RokotovD
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