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TO mitigate the detrimental effects of these oxidative radicals, the pulmonary system has developed its own defense mechanism via activating different enzyme and non-enzyme network of antioxidants like superoxide dismutase (SOD), catalase (CAT), and glutathione-based enzymes such as glutathione peroxidase (GSH-Px), glutathione S transferase (GST), glutathione reductase (GSH), glutathione synthetase, NADPH oxidase, and Rho-oxidase (Imaoka et al

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