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Gastrointestinal Disorders: Conditions like Crohn's disease, celiac disease, or a history of weight-loss surgery (like gastric bypass) can damage the exact parts of the intestine that are in charge of B12 absorption
Increased BMR & Mitochondrial Output: Enhances calorie burn and endurance potential (Kraus et al., Nature Medicine )
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In addition, if you're one the millions of Americans taking proton pump inhibitors, known as PPI's, that suppress stomach acid for conditions like acid reflux, you're going to be prone to Vitamin B12 deficiency
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