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2030 sales: $2.8 billion Aficamten (CK-274) is a next-generation cardiac myosin inhibitor for the treatment of hypertrophic cardiomyopathy
Celiac disease-related fatigue
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It was developed at the University of Arizona by Hruby and Hadley and contains two key modifications from native -MSH: a norleucine substitution at position 4 (replacing methionine) and a D-phenylalanine substitution at position 7 (replacing L-phenylalanine)
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