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The inflammatory markers monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor (TNF- ), were reduced by treatment with exendin-4 in response to lipopolysaccharide in cultured peritoneal macrophages harvested from mice [65]
"Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians"
Further studies suggested that GLP-1 stimulates both synthesis and secretion of insulin via multiple cAMP-dependent pathways
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