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Early work focused on the hGH fragment 177191, which was later modified by adding a tyrosine residue, leading to the development of AOD 9604

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HUBERMAN: And that's one of the major issues with BPC-157 that's not often discussed, which is that if you have a tumor, and tumors thrive on increased blood flow because they like to consume growth factors and increased blood flow means increased growth factors and other things that can not just sustain but actually grow the tumor, well then by taking BPC-157, you may be either maintaining or accelerating the growth of a tumor that would otherwise be removed or stay small