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While pharmaceutical companies provide conservative official guidelines to ensure maximum efficacy, real-world experiences from patients suggest some flexibility: | Storage Condition | Temperature Range | Duration ||-|-|-|| Refrigerated (unopened) | 36F to 46F (2C to 8C) | Until expiration date || Room temperature (unopened) | Up to 86F (30C) | 21 days maximum || Room temperature (after first use) | Up to 86F (30C) | 21 days maximum | Travel presents unique challenges for medication storage