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Ozempic can be highly effective when properly managed, but success depends on collaborative care between patient and clinician, realistic expectations, and appropriate lifestyle modifications alongside pharmacotherapy

Medical advice is recommended before starting management

This new trial built on a previous one published in NEJM last fall (I previously reviewed here) for the same indication, but the only difference was the inclusion of people with diabetes

Its weight loss effects are likely due to several combined actions, including appetite reduction, increased fullness, glucose regulation and changes in energy balance