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The fetuss ability to detoxify APAP by conjugation with sulfate and glucuronide remains impaired until after birth, possibly shunting more APAP through cytochrome P450

Regulation of copper homeostasis Copper homeostasis, namely, the dynamic balance in copper levels, is a tightly regulated process by various key molecules, including copper chaperones, transmembrane transporters, and transcriptional regulators (Chen et al., 2022, 2023)