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Indeed, microglial activation leads to increased production of cytokines and activation of nitric oxide synthases (iNOS)

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Brown fat AKT2 is a cold-induced kinase that stimulates ChREBP-mediated de novo lipogenesis to optimize fuel storage and thermogenesis

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Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis

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Improvement in symptoms can be seen within days to weeks of starting B12 supplementation

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