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The gap between expectation and outcome prompted a sharp decline in Novo Nordisks share price when the results were announced and opened questions about whether CagriSema could differentiate itself sufficiently from existing approved therapies

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Mechanisms of Action and Benefit Biological, Physiological, and Molecular Considerations Glucagon-like peptide 1 (GLP-1) is primarily secreted by enteroendocrine L-cells in the intestine, pancreatic -cells, and the central nervous system (CNS) [26]

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