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However, popularity online does not equal medical evidence, and it is important to understand what is known, what is uncertain, and what safer, better-studied alternatives may be available
Importantly, proteolytic cleavage of SPARC (secreted protein acidic and rich in cysteine), a matricellular protein abundantly expressed at sites of vascular injury and tissue remodeling, generates GHK-containing fragments that promote endothelial cell proliferation and neovascularization
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