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Its certainly plausible, in the same way that other medications that help with appetite, such as topiramate, have utility. The problem, said Steinglass, who also serves as director of research at the Eating Disorders Research Clinic, is that large studies of GLP-1 RAs for obesity and diabetes have not included individuals with psychiatric illnesses or EDs, leaving critical gaps in knowledge about their effects in these populations

These metabolic improvements not only support effective weight loss but also reduce long-term risks associated with diabetes, heart disease, and obesity-related complications

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Glutathione S-conjugates are usually sequestered by distinct ABC transporters from the cytosol into the vacuole for degradation, although breakdown of glutathione, oxidized glutathione and glutathione S-conjugates also happens outside the vacuole 56