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Increased concentrations of free fatty acids and their byproducts build up in peripheral nerves, causing lipotoxicity, which damages cell membrane integrity and causes neuronal cells to undergo apoptosis
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The patient reported having used an herbal preparation that was sold on several websites and was marketed as promoting regular, healthy, and complete bowel movements. Among the ingredients for this intestinal formula are aloe, senna, and cascara
Environ Microbiol 16:17091728 Morgan B, Ezeria D, Amoako TNE, Riemer J, Seedorf M, Dick TP (2013) Multiple glutathione disulfide removal pathways mediate cytosolic redox homeostasis
