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Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes
and have not been demonstrated to the FDA to be safe or effective for their intended use
Nausea affects 30 to 44% of users initially, and constipation or diarrhoea may alternate
Modest, at roughly 5 to 10 percent of body weight in responders over 56 weeks, achieved through central nervous system modulation rather than slowed gastric emptying or incretin stimulation
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