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H tr cho bnh nhn ung th : Dng bo v t bo b tn thng do bc x ion ho, phng nga tn thng t bo thn kinh, thn do tc dng c ca liu php (Cisplatin, Oxaliplatin, Cyclophosphomid, 5.FU), chng suy yu do ung th v lm chm tin trin ca bnh AIDS
In CIPN in vivo models induced by cisplatin, postmitotic sensory neurons in the dorsal root ganglion (DRG) are particularly sensitive to cisplatin injury, and axonal damage induced by cisplatin involves multiple events, including ROS generation, suggesting that antioxidants may help reduce the neurotoxicity of cisplatin [124, 125]
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