In contrast, LCA primarily inhibits apoptosis in damaged cells by disrupting mitochondrial function and mimics growth factors to activate the Wnt/-catenin pathway, thereby maintaining stem cell characteristics and driving aberrant proliferation (Farhana et al., 2016) (Figure 2A)
Moreover, GIP seems to attenuate GLP-1R-agonism mediated adverse effects thus making more tolerant this therapy and favoring WL
According to the World Health Organization (WHO), mercury and hazardous substances in cosmetics can cause kidney damage, skin rashes, discoloration, scarring, increased susceptibility to infections, anxiety, depression, psychosis, and peripheral neuropathy
Most treatment protocols run between 4 and 12 weeks, and patients often find that benefits like reduced pain, faster healing, and improved mobility persist for several months after the final injection