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Clinical trials have shown it can help people lose up to 22.5% of their body weight

The UACR detects early kidney damage (microalbuminuria) that might not yet affect serum creatinine or eGFR

Coherus said the observationcommunicated in an FDA Form 483is readily addressable and the company continues to anticipate potential approval for toripalimab by year end 2023. Coherus and its partner Junshi Biosciences received a CRL for toripalimab in this indication requesting a quality process change in May 2022

The study had no placebo group, no randomisation, no blinding, no imaging-confirmed repair endpoint and no clear analytical confirmation that the second peptide was the defined TB-500 fragment