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The effects of B12 injections typically last from one to several weeks, depending on individual health needs and lifestyle

In my experience, theres a reason patients increase their doses as recommended: they simply dont lose enough weight on the starting doses

For more on where evidence-based supplements sit in the metabolic protocol, our breakdown of PCOS weight loss supplements and vitamins covers the ones with actual PCOS trials behind them

It is important to try and not to lose muscle mass while on your weight loss journey since it is a metabolically active tissue that uses calories, your goal should be to keep as much of it as possible