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Rev Endocr Metab Disord 5: 111117, 2004
Individual responses vary, life interferes with schedules, and side effects sometimes demand adjustments
In contrast, a dysbiotic microbial configuration characterized by reduced BSH functional potential may contribute to a less efficient microbial transformation of bile acids, potentially influencing the composition of the host bile acid pool and its downstream signaling through FXR and TGR5 pathways
This practice originates from concerns about physical interactions in the gut (binding, pH changes, competition for transporters) rather than systemic pharmacokinetic conflicts
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