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We next explored the effect of combination treatment with TRAIL and BPTES, an inhibitor of glutaminase, a key enzyme in Gln metabolism, in vitro as well as in vivo in an orthotopic pancreatic tumor mouse model
Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice
The S-glutathionylation is a process in which the interaction between GSSG and cysteinyl residues of proteins results in the formation of mixed disulfides (22)
The grey bar represents the 30% level of functional hepatocytes below which liver failure is thought to occur [38]
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