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The 2024 Stanford study provided stark evidence of this, noting that the mitochondrial calcium to SOD2 (a protective enzyme) ratio was elevated by 1.67x in Long COVID donors and 1.75x in ME/CFS donors compared to healthy controls
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But trends are shifting: As of 2025, Kaiser Permanente limits coverage for GLP-1 agonists for weight management to people with a body mass index (BMI) of 40 or higher
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