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The result is selective apoptosis of FOXO4-high senescent cells, leaving FOXO4-low non-senescent cells intact a selectivity that makes it a uniquely powerful molecular probe for studying the contribution of senescent cell accumulation to tissue dysfunction, ageing phenotypes, and disease biology
However, GSH has an overall negative charge at physiological pH, and mitochondria also exhibit an enormous negative membrane potential [57, 58]
The analysis will consider policy framing and planning documents at both the national and city levels, using several Chinese cities as examples
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