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In the liraglutide group, 35% of the children experienced a BMI reduction of at least 10%, while only 4% was observed in children in the placebo group (adjusted odds ratio, 8.2 [95% CI, 1.0 to 65.3])
The tripeptide upregulates collagen I and III synthesis, stimulates angiogenesis via VEGF pathways, and modulates the NF-kB inflammatory cascade toward resolution rather than amplification
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